Elast-Eon™ biocompatible polyurethane publications
The following publications detail the work involved in the development of CSIRO’s Elast-Eon™ biocompatible polyurethane.
Patents
Gunatillake PA, McCarthy SJ, Adhikari R, Meijs GF, 2009, ‘Siloxane-Containing Polyurethane-Urea Compositions’, Publication Number US 2009/0118455 A1 – Publication Number WO/2000/064971.
Gunatillake PA, Padsalgikar A, Adhikari R, Griffiths I, Bown M, 2007, ‘Polyurethanes’, Publication Number US 2007/0027285 A1 – Publication Number WO/2005/052019.
Gunatillake PA, Meijs GF, 2006, ‘Silicon-Based Polycarbonates’, U.S. Patent Number 7,026,423 B2 – Publication Number WO/1998/054242.
Gunatillake PA, McCarthy SJ, Meijs GF, Adhikari R, 2005, ‘Shape Memory Polyurethane or Polyurethane-urea Polymers’, U.S. Patent Number 6,858,680 B2 – Publication Number WO/2001/007499.
Gunatillake PA, Meijs GF, McCarthy SJ, 2003, ‘Polysiloxane-containing polyurethane elastomeric compositions’, U.S. Patent Number 6,627,724 B2 related to U.S. Patent Number 6,313,254 B1 – Publication Number WO/1998/013405.
Gunatillake PA, McCarthy SJ, Adhikari R, Meijs GF, 2002, ‘Non-Elastomeric Polyurethane Compositions’, U.S. Patent Number 6,437,073 B1 – Publication Number WO/1999/050327.
Gunatillake PA, Meijs GF, Adhikari R, 2002, ‘Silicon-Containing Chain Extenders’, U.S. Patent Number 6,420,452 B1 – Publication Number WO/1999/003863.
Gunatillake PA, McCarthy SJ, Meijs GF, 1999, ‘Process for The Purification of Polyethers’, Publication Number WO/1999/001496.
Gunatillake PA, Meijs GF, Rizzardo E, 1995, ‘Process for the Production of Poly(alkylene oxides)’, U.S. Patent Number 5,403,912 – Publication Number WO/1992/009647.
Meijs GF, Rizzardo E, Gunatillake PA, Brandwood A, Schindhelm K, 1995, ‘Polyurethane or Polyurethane-Urea Elastomeric Compositions’, U.S. Patent Number 5,393,858 – Publication Number WO/1992/000338.
Key publications
Hernandez R, Weksler J, Padsalgaskar A, Runt J, 2008, ‘In vitro oxidation of high polydimethylsiloxane content biomedical polyurethanes: Correlation with the microstructure’, Journal of Biomedical Materials Research, 87A: 546-556.
Hernandez R, Weksler J, Padsalgikar A, Runt J, 2007, ‘Microstructural Organization of Three-Phase Polydimethylsiloxane-Based Segmented Polyurethanes’, Macromolecules, 40: 5441-5449.
Mudumba R, Padsalgikar A, Littler D, Stuart W, 2005, ‘Evaluation of aqueous extracts from Elast-Eon™ polymers for methylene dianiline (MDA) by high-performance liquid chromatography (HPLC)’, Australian Journal of Chemistry, 58: 845-850.
Simmons A, Hyvarinen J, Odell RA, Martin DJ, Gunatillake PA, Noble KR, Poole-Warren LA, 2004, ‘Long-term in vivo Biostability of Poly(dimethylsiloxane)/Poly(hexamethylene oxide) Mixed Macrodiol based Polyurethane Elastomers’, Biomaterials, 25: 4887-4900.
Adhikari R, Gunatillake PA, Bown M, 2003, ‘Effect of Poly(dimethylsiloxane) on morphology and properties of Polyurethanes and Polyurethaneureas’, Journal of Applied Polymer Science, 90: 1565-1573.
Adhikari R, Gunatillake PA, Mejis GF, McCarthy SJ, 2003, ‘Low Modulus Siloxane-Based Polyurethanes: Part II- Effect of the chain extender on Properties and Morphology’, Journal of Applied Polymer Science, 87: 1092-1100.
Adhikari R, Gunatillake PA, Mejis GF, McCarthy SJ, 2002, ‘Low Modulus Siloxane-Based Polyurethanes: Part I- Effect of the chain extender 1,3-bis(4-hydroxybutyl)1,1,3,3-tetramethyldisiloxane on Properties and Morphology’, Journal of Applied Polymer Science, 83: 736-746.
Adhikari R, Gunatillake PA, et al., 2000, ‘Mixed Macrodiol-based Siloxane Polyurethanes: Effect of the Comacrodiol Structure on Properties and Morphology’, Journal of Applied Polymer Science, 78: 1071-1082.
Gunatillake PA, Meijs GF, Adhikari R, et al., 2000, ‘Poly(dimethylsiloxane)/poly(hexamethylene oxide) mixed macrodiol based polyurethane elastomers: I- Synthesis and properties’, Journal of Applied Polymer Science, 76: 2026-2040.
Martin DJ, Poole-Warren LA, Gunatillake PA, McCarthy SJ, Meijs GF, Schindhelm K, 2000, ‘Polydimethylsiloxane/Polyether -mixed Macrodiol-based Polyurethane Elastomers: Biostability’, Biomaterials, 21: 1021-1029.
Adhikari R, Gunatillake PA, McCarthy SJ, Meijs GF, 1999, ‘The Effect of Chain Extender Structure on Properties and Morphology of Polyurethanes Based on H12MDI and Mixed Macrodiols (PDMS/PHMO)’, Journal of Applied Polymer Science, 74: 2979-2989.
Adhikari R, Gunatillake PA, Meijs GF, McCarthy SJ, 1999, ‘The Effect of Diisocyanate Isomer Composition on Properties and Morphology of Polyurethanes Based on 4,4′-dicyclohexyl Methane Diisocyanate and Mixed Macrodiols (PDMS-PHMO)’, Journal of Applied Polymer Science, 73: 573-582.
Martin DJ, Meijs GF, et al., 1999, ‘The Influence of Composition Ratio on the Morphology of Biomedical Polyurethanes’, Journal of Applied Polymer Science, 71: 937-952.
Gunatillake PA, Meijs GF, McCarthy SJ, Adhikari R, Sherrif N, 1998, ‘Synthesis and Characterization of a series of Poly(alkylene carbonate) Macrodiols and the Effect of Their Structure on the Properties of Polyurethanes’, Journal of Applied Polymer Science, 68: 1621-1633.
Gunatillake PA, Meijs GF, Mccarthy SJ, Sherrif N, 1997, ‘Polyurethane Elastomers with Low Modulus and Hardness Based on Novel Copolyether Macrodiols’, Journal of Applied Polymer Science, 63: 1373-1384.
Hunt JA, Meijs GF, Williams DF, 1997, ‘Hydrophilicity of Polymers and Soft Tissue Responses: A Quantative Analysis’, Journal of Biomedical Materials Research, 36: 542-549.
McCarthy SJ, Meijs GF, Mitchell N, Gunatillake PA, Graeme H, Brandwood A, Schindhelm K, 1997, ‘In vivo Degradation of polyurethanes: Transmission -FTIR Microscopic Characterization of Polyurethanes Sectioned by Cryomicroscopy’, Biomaterials, 18: 1387-1409.
McCarthy SJ, Meijs GF, Gunatillake PA, 1997, ‘Synthesis, Characterization, and Stability of Poly(alkylene oxide)esterThermoplastic Elastomers’, Journal of Applied Polymer Science, 65: 1319-1332.
Martin DJ, Meijs GF, Gunatillake PA, Renwick GM, McCarthy SJ, 1997, ‘Effect of Average Soft Segment Length on Morphology and Properties of a Series of Polyurethane Elastomers. II. SAXS-DSC Annealing Study’, Journal of Applied Polymer Science, 64: 803-817.
Martin DJ, Meijs GF, Renwick GM, Gunatillake PA, McCarthy SJ, 1996, ‘Effect of Soft-segment CH2/O Ratio on Morphology and Properties of a Series of Polyurethane Elastomers’, Journal of Applied Polymer Science, 60: 557-571.
Brandwood A, Meijs GF, Gunatillake PA, Noble KR, Schindhelm K, Rizzado E, 1994, ‘In Vivo Evaluation of Polyurethanes Based on Novel Macrodiols and MDI’, Journal of Biomaterials Science, Polymer Edition, 6: 41-54.
Gunatillake PA, Meijs GF, Rizzardo E, McCarthy SJ, Chatelier RC, Brandwood A, Schindhelm K, 1993, ‘Novel Polyetherurethaneurea Elastomers Based on a,a,a,a-Tetramethyl-m-xylenediisocyanate: Synthesis, Characterization, Processability and Hydrolytic Stability’, Journal of Applied Polymers, 47: 199-210.
Brandwood A, Noble KR, Schindhelm K, Meijs GF, Gunatillake PA, Chatelier RC, McCarthy SJ, Rizzardo E, 1992, ‘A Comparison of in Vivo Degradation of novel Polyurethanes with Performance in Vitro Accelerated Tests’, In: Degradation Phenomena in Polymeric Biomaterials, Dauner M (ed), Springer-Verlag, Berlin, pp.59-66.
Brandwood A, Noble KR, Schindhelm K, Meijs GF, Gunatilake PA, Chatelier RC, McCarthy SJ, Rizzardo E, 1992, ‘Influence of Stress on Novel biomedical Polyurethanes’, Advanced Biomaterials, 10: 413-419.
Gunatillake PA, Meijs GF, et al., 1992, ‘Polyurethane Elastomers Based on Novel Polyether Macrodiols and MDI: Sysnthesis, Mechanical Properties, and Resistance to Hydrolysis and Oxidation’, Journal of Applied Polymer Science, 46: 319-328.
Gunatillake PA, Meijs GF, Chatelier RC, McIntosh DM, Rizzardo E, 1992, ‘Synthesis and Characterization of
Hydroxy-Terminated Poly(alkylene oxides) by Condensation Polymerization’, Polymer International, 27: 275-283.
Reviews
Gunatillake PA, Mayadunne R, Adhikari R, 2006, ‘Recent Developments in Synthetic Biodegradable Polymers’, Biotechnology Annual Reviews, 12: 301-347.
Gunatillake PA, Adhikari R, 2003, ‘Biodegradable Synthetic Polymers for Tissue Engineering’, European Cells & Materials, 5: 1-16.
Gunatillake PA, Martin DJ, Meijs GF, McCarthy SJ, Adhikari R, 2003, ‘Designing Biostable Polyurethane Elastomers for Biomedical Implants’, Australian Journal of Chemistry, 56: 545-557.
Gunatillake PA, Meijs GF, McCarthy SJ, 2001, ‘Commercial Production of Polyurethanes’, In: Biomedical Applications of Polyurethanes, Vermette, Griesser, Laroche, Guidoin, Landes (eds), Bioscience, Texas, pp.22-48.
Gunatillake PA, Meijs GF, McCarthy SJ, 2001, ‘Developments in Design and Synthesis of Biostable Polyurethanes’, In: Biomedical Applications of Polyurethanes, Vermette, Griesser, Laroche, Guidoin, Landes (eds), Bioscience, Texas, pp.160-170.
Gunatillake PA, Meijs GF, 2001, ‘Polyurethanes in Biomedical Engineering’, In: Encyclopaedia of Materials: Science and Technology, Elsevier Science, pp.7746-7753.