Hendra virus publications

By October 22nd, 2010

The following publications detail the work involved in the development of CSIRO’s Hendra virus identification.

Key publications

Bonaparte MI, Dimitrov AS, Bossart KN, Crameri GS, Mungall BA, Bishop KA, Choudhry V, Dimitrov DS, Wang LF, Eaton BT, Broder CC, 2005, ‘Ephrin-B2 ligand is a functional receptor for Hendra virus and Nipah virus’, Proc. National Academy Sciences, USA, 102: 10652-10657.

Chua KB, Bellini WJ, Rota PA, Harcourt BH, Tamin A, Lam Sai Kit K, Ksiazek TG, Rollin PE, Zaki SR, Shieh WJ, Goldsmith CS, Gubler DJ, Roehrig JT, Eaton BT, Gould AR, Olson J, Field HE, Daniels PW, Ling AE, Peters CJ, Anderson LJ, Mahy BWJ, 2000, ‘Nipah virus: a recently emergent deadly paramyxovirus’, Science, 288: 1432-1435.

Wang LF, Yu M, Hansson E, Pritchard LI, Shiell BJ, Michalski WP, Eaton BT, 2000, ‘The exceptionally large genome of Hendra virus: support for creation of a new genus within the family paramyxoviridae’, _Journal of Virology, 74: 9972-9979.

O’Sullivan JD, Allworth AM, Paterson DL, Snow TM, Boots R, Gleeson LJ, Gould AR, Hyatt AD, Bradfield J, 1997, ‘Fatal encephalitis due to novel paramyxovirus transmitted from horses’, Lancet, 349: 93-95.

Hooper PT, Gould AR, Russell GM, Kattenbelt JA, Mitchell G, 1996, ‘The retrospective diagnosis of a second outbreak of Equine Morbillivirus infection’, Australian Veterinary Journal, 74: 244-245.

Rogers RJ, Douglas IC, Baldock FC, Glanville RJ, Seppanen KT, Gleeson LJ, Selleck PW, Dunn KJ, 1996, ‘Investigation of a second focus of Equine Morbillivirus infection in coastal Queensland’, Australian Veterinary Journal, 74: 243-244.

Murray PK, Selleck PW, Hooper PT, Hyatt AD, Gould AR, Gleeson LJ, Westbury HA, Hiley L, Selvey LA, Rodwell BJ, Ketterer PJ, 1995, ‘A Morbillivirus that caused fatal disease in horses and humans’, Science, 268: 94-97.

Selvey LA, Wells RM, McCormack JG, Ansford AJ, Murray PK, Rogers RJ, Lavercombe PS, Selleck PW, Sheridan JW, 1995, ‘Infection of humans and horses by a newly described Morbillivirus’, Medical Journal of Australia, 162: 642-645.

Westbury HA, Hooper PT, Selleck PW, Murray PK, 1995, ‘Equine Morbillivirus pneumonia: susceptibility of laboratory animals to the virus’, Australian Veterinary Journal, 72: 278-279.


Eaton BT, Wang LF, 2008, ‘Henipaviruses’, In: Encyclopedia of Virology, Elsevier, Netherlands, pp.321-327.

MacKenzie JS, Childs JE, Field HE, Wang LF, Breed AC, 2008, ‘The role of bats as reservoir hosts of emerging neurological viruses’, In: Neurotropic Viral Infections, Cambridge University Press, Cambridge, UK, pp.382-406.

Wang LF, MacKenzie JS, Eaton BT, 2008, ‘Disease outbreaks caused by emerging paramyxoviruses of bat origin’, In: Emerging Infections in Asia, Springer, New York, pp.193-208.

Eaton BT, Mackenzie JS, Wang LF, 2007, ‘Henipaviruses’, In: Fields Virology, Wolters Kluwer, Philadelphia, USA, pp.1587-1600.

Eaton BT, Broder CC, Middleton DJ, Wang LF, 2005, ‘Hendra and Nipah viruses: different and dangerous’, Nature Reviews: Microbiology, 4: 23-35.

Eaton BT, Broder CC, Wang LF, 2005, ‘Hendra and Nipah viruses: pathogenesis and therapeutics’, Current Molecular Medicine, 5: 805-816.

Hooper PT, Zaki SR, Daniels PW, Middleton DJ, 2001, ‘Comparative pathology of the diseases caused by Hendra and Nipah viruses’, Microbes and Infection, 3: 315-322.

Hyatt AD, Zaki SR, Goldsmith CS, Wise T, Hengstberger SG, 2001, ‘Ultrastructure of Hendra virus and Nipah virus within cultures cells and host animals’, Microbes and Infection, 3: 297-306.

MacKenzie JS, Chua KB, Daniels PW, Eaton BT, Field HE, Hall RA, Halpin K, Johansen CA, Kirkland PD, Lam Sai Kit K, McMinn P, Nisbet DJ, Paru R, Pyke AT, Ritchie SA, Siba P, Smith DW, Smith GA, Van den Hurk AF, Wang LF, Williams DT, 2001, ‘Emerging viral diseases of South East Asia and the Western Pacific’, Emerging Infectious Diseases, 7(supplement): 497-504.

Wang LF, Harcourt BH, Yu M, Tamin A, Rota PA, Bellini WJ, Eaton BT, 2001, ‘Molecular biology of Hendra and Nipah viruses’, Microbes and Infection, 3: 279-287.

Daszak P, Cunningham AA, Hyatt AD, 2000, ‘Emerging infectious diseases of wildlife – Threats to biodiversity and human health’, Science, 287: 443-449.

Murray PK, Rogers RJ, Selvey LA, Selleck PW, Hyatt AD, Gould AR, Gleeson LJ, Hooper PT, Westbury HA, 1995, ‘A novel Morbillivirus pneumonia of horses and its transmission to humans’, Emerging Infectious Diseases, 1: 31-33.

Original papers

Kaku Y, Noguchi A, Marsh GA, McEachern JA, Okutani A, Hotta, K, Bazartseren B, Fukushi S, Broder CC, Yamada A, Inoue S, Wang LF, 2009, ‘A neutralization test for specific detection of Nipah virus antibodies using pseudotyped vesicular stomatitis virus expressing green fluorescent protein’,_ Journal of Virological Methods_, 160: 7-13.

Lo M, Harcourtm BH, Mungall BA, Tamin A, Peeples ME, Bellini WJ, Rota P, 2009, ‘Determination of the Henipavirus phosphoprotein gene mRNA editing frequencies and detection of the C, V, and W proteins of Nipah virus in virus infected cells’, Journal of General Virology, 90: 398-404.

Bossart KN, Tachedjian M, McEachern JA, Crameri G, Zhu Z, Dimitrov DS, Broder CC, Wang LF, 2008, ‘Functional studies of host-specific ephrin-B ligands as Henipavirus receptors’, Virology, 372: 357-371.

Epstein JH, Prakash V, Smith CS, Daszak P, McLaughlin AB, Meehan G, Field HE, Cunningham AA, 2008, ‘Henipavirus Infection in Fruit Bats (Pteropus giganteus), India’, Emerging Infectious Diseases, 14: 1309-1311.

Hayman DT, Suu-Ire R, Breed AC, McEachern JA, Wang L , Wood JL, Cunningham AA, 2008, ‘Evidence of henipavirus infection in West African fruit bats’, PLoS ONE, 3: e2739.

McEachern JA, Bingham J, Crameri G, Green DJ, Hancock TJ , Middleton D, Feng YR, Broder CC, Wang LF, Bossart KN, 2008, ‘A recombinant subunit vaccine formulation protects against lethal Nipah virus challenge in cats’, Vaccine, 26: 3842-3852.

Patch JR, Han Z, McCarthy SE, Yan L, Wang LF, Harty RN, Broder CC, 2008, ‘The YPLGVG sequence of the Nipah virus matrix protein is required for budding’, Virology Journal, 5: 137.

Bishop KA, Stantchev TS, Hickey AC, Khetawat D, Bossart KN, Krasnoperov V, Gill P, Feng YR, Wang LF, Eaton BT, Broder CC, 2007, ‘Identification of Hendra virus G glycoprotein residues that are critical for receptor binding’, Journal of Virology, 81: 5893-5901.

Magoffin DE, Halpin K, Rota PA, Wang LF, 2007, ‘Effects of single amino acid substitutions at the E residue in the conserved GDNE motif of the Nipah virus polymerase (L) protein’, Archives of Virology, 152: 827-832.

Mungall BA, Middleton D, Crameri G, Halpin K, Bingham J, Eaton BT, Broder CC, 2007, ‘Vertical transmission and fetal replication of Nipah virus in an experimentally infected cat’, Journal of Infectious Diseases, 196: 812-816.

Patch JR, Crameri GS, Wang LF, Eaton BT, Broder CC, 2007, ‘Quantitative analysis of Nipah virus proteins released as virus-like particles reveals central role for the matrix protein’, Virology Journal, 4: 1-36.

Wang LF, Hansson E, Yu M, Chua KB, Mathe N, Crameri G, Rima BK, Moreno-Lopez J, Eaton BT, 2007, ‘Full-length genome sequence and genetic relationship of two paramyxoviruses isolated from bat and pigs in the Americas’, Archives of Virology, 152: 1259-1271.

Epstein JH, Rahman SA, Zambriski JA, Halpin K, Meehan G, Aziz J, Sharifah SH, Field HE, Hyatt AD, Daszak P, 2006, ‘Feral cats and risk for Nipah virus transmission’, Emerging Infectious Diseases, 12: 1178-1179.

Hagmaier K, Stock N, Goodbourn S, Wang LF, Randall R, 2006, ‘A single amino acid substitution in the V protein of Nipah virus alters its ability to block interferon signalling in cells from different species’, Journal of General Virology, 87: 3649-3653.

Mungall BA, Middleton DJ, Crameri GS, Bingham J, Halpin K, Russell GM, Green D, McEachern JA, Pritchard LI, Eaton BT, Wang LF, Bossart KN, Broder CC, 2006, ‘A feline model of acute Nipah virus infection and protection with a soluble glycoprotein-based subunit vaccine’, Journal of Virology, 80: 12293-12302.

Zhu Z, Dimitrov AS, Bossart KN, Crameri GS, Bishop KA, Choudhry V, Mungall BA, Feng YR, Choudhary A, Zhang MY, Feng YR, Wang LF, Xiao X, Eaton BT, Broder CC, Dimitrov DS, 2006, ‘Potent neutralization of Hendra and Nipah viruses by human monoclonal antibodies’, Journal of Virology, 80: 891-899.

Bossart KN, Crameri GS, Dimitrov AS, Mungall BA, Feng YR, Patch JR, Choudhary A, Wang LF, Eaton BT, Broder CC, 2005, ‘Receptor binding, fusion inhibition and induction of cross-reactive neutralizing antibodies by a soluble G glycoprotein of Hendra virus’, Journal of Virology, 79: 6690-6702.

Bossart KN, Mungall BA, Crameri GS, Wang LF, Eaton BT, Broder CC, 2005, ‘Inhibition of Henipavirus fusion and infection by Heptad-derived peptides of Nipah virus fusion protein’, Virology Journal, 2: 57.

Weingartl HM, Czub S, Copps J, Berhane Y, Middleton DJ, Marszal P, Gren J, Smith GA, Ganske S, Manning L, Czub M, 2005, ‘Invasion of the central nervous system in a porcine host by Nipah virus’, Journal of Virology, 79: 7528-7534.

Wright PJ, Crameri GS, Eaton BT, 2005, ‘RNA synthesis during infection by Hendra virus: an examination by quantitative real-time PCR of RNA accumulation, the effect of ribavirin and the attenuation of transcription’, Archives of Virology, 150: 521-532.

Chan YP, Koh CL, Lam Sai Kit K, Wang LF, 2004, ‘Mapping of domains responsible for nucleocapsid protein-phosphoprotein interaction of Henipaviruses’, Journal of General Virology, 85: 1675-1684.

Bossart KN, Wang LF, Flora, MN, Chua, KB, Lam Sai Kit, K, Eaton BT, Broder CC, 2002, ‘Membrane fusion tropism and heterotypic functional activities of the Nipah virus and Hendra virus envelope glycoproteins’, Journal of Virology, 76: 11186-11198.

Crameri GS, Wang LF, Morrissy CJ, White JR, Eaton BT, 2002, ‘A rapid immune plaque assay for the detection of Hendra and Nipah viruses and anti-virus antibodies’,_ Journal of Virological Methods_, 99: 41-51.

Bossart KN, Wang LF, Eaton BT, Broder CC, 2001, ‘Functional expression and membrane fusion tropism of the envelope glycoproteins of Hendra virus’, Virology, 290: 121-135.

Black PF, Cronin JP, Morrissy CJ, Westbury HA, 2001, ‘Serological examination for evidence of infection with Hendra and Nipah viruses in Queensland piggeries’, Australian Veterinary Journal, 79: 424-426.

Yob JM, Field HE, Rashdi AM, Morrissy CJ, Van der Heide B, Rota PA, Binadzhar A, White JR, Daniels PW, Aziz AJ, Ksiazek TG, 2001, ‘Nipah virus infection in bats (order Chiroptera) in peninsular Malaysia’, Emerging Infectious Diseases, 7: 439-441.

Michalski WP, Crameri GS, Wang LF, Shiell BJ, Eaton BT, 2000, ‘The cleavage activation and sites of glycosylation in the fusion protein of Hendra virus’, Virus Research, 69: 83-93.

Westbury HA, 2000, ‘Hendra virus: a highly lethal zoonotic agent’, Veterinary Journal, 160: 165-166.

Hooper PT, Russell GM, Selleck PW, Lunt RA, Morrissy CJ , Braun MA, Williamson MM, 1999, ‘Immunohistochemistry in the identification of a number of new diseases in Australia’, Veterinary Microbiology, 68: 89-93.

Wang LF, Michalski WP, Yu M, Pritchard LI, Crameri GS, Shiell BJ, Eaton BT, 1998, ‘A novel P/V/C gene in a new member of the paramyxoviridae family, which causes lethal infection in humans, horses, and other animals’, Journal of Virology, 72: 1482-1490.

Yu M, Hansson E, Langedijk JPM, Eaton BT, Wang LF, 1998, ‘The attachment protein of Hendra virus has high structural similarity but limited primary sequence homology compared with viruses in the genus Paramyxovirus’, Virology, 251: 227-233.

Yu M, Hansson E, Shiell BJ, Michalski WP, Eaton BT, Wang LF, 1998, ‘Sequence analysis of the Hendra virus nucleoprotein gene: comparison with other members of the subfamily paramyxoviridae’, Journal of General Virology, 79: 1775-1780.

Hooper PT, Ketterer PJ, Hyatt AD, Russell GM, 1997, ‘Lesions of experimental Equine Morbillivirus pneumonia in horses’, Veterinary Pathology, 34: 312-322.

Hooper PT, Westbury HA, Russell GM, 1997, ‘The lesions of experimental Equine Morbillivirus disease in cats and guinea pigs’, Veterinary Pathology, 34: 323-329.

Wang LF, Gould AR, Selleck PW, 1997, ‘Expression of Equine Morbillivirus (EMV) matrix and fusion proteins and their evaluation as diagnostic reagents’, Archives of Virology, 142: 2269-2279.

Westbury HA, Hooper PT, Brouwer SL, Selleck PW, 1996, ‘Susceptibility of cats to Equine Morbillivirus’, Australian Veterinary Journal, 74: 132-134.